drug dosage guidelines veterinary saunders manual | Page 5

g/kg of 15–25% solution
over 15–60 minutes IV (repeat in 4–6 hours if necessary)
Marbofloxacin
Marbocyl, Zeniquin
Dog: 2.75–5.55mg/kg q24h PO
Mebendazole
Telmintic
22mg/kg (with food) q24h for 3 days
Meclizine hydrochloride
Bonine
Dog: 25mg/dog q24h PO (motion sickness:
administer 1 hour before traveling)
Cat: 12.5mg/cat q24h PO
Meclofenamic acid
Meclomen
Meclofen
Arquel
Dog: 1mg/kg/d for 5 days, then 0.5mg/kg q24h PO
Medetomidine
Domitor
Dog: 0.007–0.02 mg/kg IV; 0.01–0.04mg/kg IM, SC
Cat: 0.01–0.03mg/kg IV; 0.03–0.08mg/kg IM, SC
Medium-chain triglycerides (MCTs)
MCT oil
1–2ml/kg daily in food
Medroxyprogesterone acetate
Depo-Provera
1.1–2.2mg/kg q7d IM
Megestrol acetate
Ovaban
Dog: Proestrus: 2.2 mg/kg q24h PO for 8 days
Anestrus: 0.55 mg/kg q24h PO for 30 days Behavior
problems: 2–4 mg/kg q24h for 8 days (reduce dose
for maintenance)
Cat: dermatologic therapy or urine spraying: 2.5–
5.0 mg/cat q24h PO for 1 week, then reduce to 2.5–
5.0 mg once or twice/wk; suppress estrus: 5mg/cat
for 3 days, then 2.5–5 mg once/wk for 10 weeks
Melarsomine
Immiticide
Dog: 2.5 mg/kg, IM, q24h for 2 doses, Alternate:
2.5 mg/kg, IM once; then after 1–2 months give
2.5 mg/kg IM, q24h for 2 additional doses
Meloxicam
Metacam
Dog: 0.2 mg/kg PO, SC initially, then 0.1 mg/kg q24h
for 2–3 days
Cat: 0.3 mg/kg SC, one time only
Melphalan
Alkeran
2–4mg/m2 q24–48h PO (see Chap. 26)
Meperidine
Demerol
Dog: 0.4–2mg/kg IV, 1.0–4.0mg/kg IM, SC

6-Mercaptopurine
Purinethol
50mg/m2 q24h PO
Mesalamine
Asacol; Pentasa
Dogs: 20mg/kg q8–12h PO
(See also Osalazine sodium; Sulfasalazine)
Metaproterenol
Alupent
Metaprel
0.325–0.65mg/kg q4–6h PO
Metaraminol bitartrate
Aramine
0.1mg/kg IM, SC
Methazolamide
Neptazane
2–4mg/kg q8–12h PO
Methenamine hippurate
Hiprex
Dog: 500mg/dog q12h PO
Cat: 250mg/cat q12h PO
Methenamine mandelate
Mandelamine
10–20mg/kg q8–12h PO
Methimazole
Tapazole
Cat: 2.5 mg/cat q8–12h PO (initial), increase to
5–10mg/cat q8–12h PO by monitoring T4
Methionine (l-methionine, dl-methionine)
Uroeze
Methio-Form
Dog: 150–300mg/kg/d PO
Cat: 1000–1500mg/cat PO (added to food each day)
(use in adult cats only)
Appendix 1953
Methocarbamol
Robaxin-V
44mg/kg q8h PO on the first day, then 22–44mg/kg q8h
PO
Methotrexate (MTX)
2.5mg/m2 q24h PO; or 2–3 times per week;
15–20mg/m2 IV q3wk (see Chap. 26)
Methoxamine
Vasoxyl
200–250mg/kg IM, or 40–80mg/kg IV
Methscopolamine bromide
Pamine
0.3–1.0 mg/kg q8h PO (use cautiously in cats)
Methylene blue (1% solution)
Dog: for pancreatic tumor identification: 3mg/kg IV
slowly, diluted in isotonic saline (can cause hemolytic
anemia)
Cat: do not use
Methylprednisolone
Medrol
Dog: 0.22–0.44mg/kg q12–24h PO
Methylprednisolone acetate
Depo-Medrol
Dog: 1mg/kg IM q1–3wk
Cat: 10–20mg/cat IM q1–3wk
Methylprednisolone sodium succinate
Solu-Medrol

For spinal cord trauma: 30mg/kg IV, repeat at 15mg/kg IV
in 2–6 hours
4-Methylpyrazole (fomepizole)
Antizol-Vet
20mg/kg initially IV, then 15 mg/kg at 12- and 24-hour
intervals, then 5 mg/kg at 36h.
Methyltestosterone
Android
Fluoxymestrone
Dog: 1.0mg/kg q48h PO
(see also Testosterone cypionate; Testosterone propionate),
for sex hormone dematoses in dogs: 1 mg/kg (up to
30mg total dose)
Cat: 1.0–2.5mg/cat q48h PO
Metoclopramide
Reglan
Maxolon
0.2–0.5mg/kg q6–8h IV, IM, SC, PO, or 1–2mg/kg q24h via
continuous IV infusion
Metoprolol tartrate
Lopressor
Dog: 5–50mg/dog q8h PO
Cat: 2–15mg/cat q8h PO
or: 0.25–1.0mg/kg q8h PO (dog and cat)
Metronidazole
Flagyl
Dog: for giardia: 50–65 mg/kg q24h PO for 5–7 days;
Antibacterial: 10–15mg/kg q8–12h PO
Cat: for giardia: 50 mg/kg q24h PO for 5 days;
Antibacterial: 10mg/kg q8h or 15mg/kg q12h PO
Mexiletine
Mexitil
Dog: 5–8mg/kg q8–12h PO (use cautiously)
Mibolerone
Cheque
Dog: (2.6–5.0mg/kg/d PO) 0.45–11.3 kg: 30mg
11.8–22.7 kg: 60mg 23–45.3 kg: 120mg >45.8 kg: 180mg
Cat: safe dose not established
Midazolam
Versed
0.1–0.25mg/kg IV, IM, or 0.1–0.3 mg/kg/h IV infusion
Milbemycin oxime
Interceptor
Dog: 0.5mg/kg q30d PO
For demodex: 1–2mg/kg q24h PO
For scabies: 2 mg/kg PO twice at 14-day intervals
Milk of magnesia
See Magnesium hydroxide
Milk thistle
Marin
6–100mg q24h PO
Minocycline
Minocin
5.0–12.5mg/kg q12h PO
Misoprostol
Cytotec
Dog: 3–5mg/kg q6–8h PO
Mitotane (o,p¢-DDD)
Lysodren
For pituitary-dependent hyperadrenocorticism: 50mg/kg/d
PO (may be given in divided doses) for 5–10 days, then
50–70mg/kg/wk PO

Adrenal tumor: 50–75 mg/kg/d for 10 days PO, then 75–100
mg/kg/wk PO (see Chap. 33)
Mitoxantrone
Novantrone
5–6mg/m2 IV q3wk
Morphine
Dog: 0.2–0.6 mg/kg IM, SC (as needed); 0.1mg/kg
epidural
Cat: 0.1 mg/kg IM, SC (as needed)
Nadolol
Corgard
0.25–0.5mg/kg q12h PO
Nafcillin sodium
Unipen
10mg/kg q6h IM, PO
Nalbuphine
Dog: 0.5–2.0mg/kg IV, IM, SC
Cat: 0.5–1.5mg/kg IV, IM, SC
Nalorphine
Nalline
0.44mg/kg IV, IM, SC (1 mg for every 10 mg of morphine)
Naloxone
Narcan
0.003–0.01mg/kg IV, IM, for opiate reversal
Naltrexone hydrochloride
Trexan
Behavior problems: 2.2mg/kg q12h PO
Nandrolone decanoate
Deca-Durabolin
Dog: 1.0–1.5mg/kg qwk IM
Cat: 1mg/cat qwk IM
1954 Appendix
Neomycin
Biosol
10–20mg/kg q6–12h PO
Neostigmine bromide
Prostigmin bromide
2mg/kg/d PO (in divided doses, to effect)
Neostigmine methylsulfate
Prostigmin
Antimyasthenic: 10mg/kg IM, SC, as needed (atropine may
be administered to counteract side effects)
Antidote for curiform block: 40mg/kg IM, SC (administer
with atropine)
Diagnostic aid for myasthenia gravis: 40mg/kg IM, or
20mg/kg IV
Nitrofurantoin
Furadantin
Macrodantin
4mg/kg q8h PO