drug dosage guidelines veterinary saunders manual | Page 4

or 44U/kg once IM
Cat: 250U/cat once IM
Gonadotropin-releasing hormone
See Gonadorelin
Griseofulvin (microsize)
Fulvicin U/F powder or tablets
50mg/kg q24h PO (maximum dose: 110–132mg/kg/d in
divided treatments)
Griseofulvin (ultramicrosize)
Fulvicin P/G
5–10mg/kg/d PO (in divided treatments)
Growth hormone
0.1 U/kg 3 times/wk for 4–6 weeks
Halothane
Fluothane
3% (induction); 0.5–1.5% (maintenance) (see Chap. 2)
Heparin sodium
Liquaemin (U.S.)
Hepalean (Canada)
100–200U/kg IV, loading dose; then 100–300U/kg q6–8h
SC (monitor clotting profiles)
Low-dose therapy (dog and cat): 70U/kg q8–12h SC
Hetacillin potassium
Hetacin-K
20–40mg/kg q8h PO
Hetastarch
See Hydroxyethyl starch
Hydralazine
Apresoline
Dog: 0.5 mg/kg (initial dose), titrated to 0.5–2.0
mg/kg q12h PO
Cat: 2.5–5mg/cat q12–24h PO
Hydrochlorothiazide
Hydrodiuril
2–4mg/kg q12h PO
Hydrocodone
Hycodan
Dog: 0.22mg/kg q6–12h PO
Hydrocortisone
Cortef
Replacement therapy: 1mg/kg q12h PO
Anti-inflammatory: 2.5–5.0mg/kg q12h PO
Hydrocortisone sodium succinate
Solu-Cortef
Shock: 50–150mg/kg IV

Hydromorphone
0.1–0.2mg/kg IV, IM, SC
Hydroxyethyl starch
Hetastarch
Dog: 20ml/kg/24h (5ml/kg over 15 min for
hypovolemia) (see Chap. 5)
Cat: 10ml/kg/24h (2.5ml/kg over 15 min for
hypovolemia) (see Chap. 5)
Hydroxyurea
Hydrea
For polycythemia vera: 30 mg/kg/d for 1 week, then
15mg/kg/d until remission
Hydroxyzine
Atarax
Dog: 2.2mg/kg q8–12h PO
Cat: 10mg/cat q12h PO
Hyoscyamine
0.003–0.006mg/kg q8–12h PO, SC
Imidocarb
5mg/kg IM SC once and repeated in 14 days
Imipramine
Dog: 1mg/kg q8h PO
Cat: 2.5–5.0mg/cat q12h PO
Insulin (NPH isophane)
Dog: 0.5–1.0 U/kg q12–24h SC (to effect)
Cat: 1–5U/cat q12h SC (to effect) (see Chap. 34)
Insulin (PZI)
Dog: 0.5–1.0 U/kg q12–24h SC (to effect)
Cat: 1–5 units/cat (0.2–1.0U/kg) q12–24h SC
(adjust with monitoring) (see Chap. 34)
Insulin (regular crystalline)
Ketoacidosis:
See Chapter 34 for complete treatment protocol
Insulin, ultralente
Dog: 0.5–1.0 U/kg q12–24h SC (to effect)
Cat: 1–5U/cat q12–24h SC (to effect) (see Chap. 34)
Interferon-alpha
Roferon A; Intron A (dilute to 30U/ml)
Cat: 30U/cat q24h for 7 days on alternating weeks
Appendix 1951
Interferon-omega (recombinant feline [rFeIFN-omega])
Virbagen
FIP: 1,000,000 u/kg SC (See Chapters 8–10 and 14 for
treatment protocols)
Iodide
See Potassium iodide
Ipecac syrup
Dog: 1–2ml/kg up to 15ml PO
Cat: 2–6ml/cat PO
Iron
See Ferrous sulfate
Isoflurane
3.5% (induction); 1.5–2.5% (maintenance)
(see Chap. 2)
Isoproterenol
Isuprel
0.04–0.09mg/kg/min IV; 0.1–0.2mg/dog q4–6h IM, SC
Isosorbide dinitrate
Isordil
Sorbitrate
2.5–5mg/animal q12h PO
Isotretinoin

Accutane
1–3mg/kg/d (maximum dose: 3–4mg/kg/d) PO
Itraconazole
Sporanox
Dog: 5mg/kg q12–24h PO
Cat: 5–10mg/kg q12h PO, or 20mg/kg q24h
Ivermectin
Heartgard
Ivomec
Heartworm preventive in dog: 6mg/kg q30d PO
Cat: 24mg/kg q30d PO
Microfilaricide in dog: 50mg/kg PO 3–4 weeks after
adulticide therapy
Ectoparasite therapy: 300–600mg/kg q24h IM, SC, PO
(do not use in collie and sheltie dogs)
Respiratory parasites: 200–400mg/kg weekly SC, PO (do not
use in collie and sheltie dogs)
Kanamycin sulfate
Kantrim
10mg/kg q6–8h IV, IM, SC
Kaolin plus pectin
Kaopectate
1–2ml/kg q2–6h PO
Ketamine
Ketalar
Ketaset
Cat: 4–10mg/kg IV, 10–20 mg/kg IM, SC (see Chap 2)
Dog: 1ml/10kg IV of ketamine : diazepam mixture
(50 : 50)
Ketoconazole
Nizoral
Dog: 10–15mg/kg q12h PO (Malassezia canis
infection: 10mg/kg q24h or 5mg/kg q12h PO)
Hyperadrenocorticism: 15mg/kg q12h PO
Cat: 5–10mg/kg q8–12h PO
Ketoprofen
Ketofen
Dog: 1.1mg/kg q24h IV, PO for up to 5 days
Cat: 2mg/kg q24h PO, SC initially, then 0.5–1.0 PO, SC
Lactated Ringer’s solution
40–50ml/kg/d IV for maintenance requirements
Shock therapy:
Dog: 90ml/kg IV
Cat: 60ml/kg IV
Lactulose
Cephulac; Duphalac
Constipation: 1ml/4.5kg q8h PO (to effect)
Hepatic encephalopathy
Dog: 0.5ml/kg q8h PO
Cat: 2.5–5.0ml/cat q8h PO
Leucovorin (folinic acid)
Wellcovorin
With methotrexate administration: 3mg/m2 IV, IM, PO
Antidote for pyrimethamine toxicosis: 1mg/kg q24h PO
Levamisole
Levasole
Tramisol
Dog: 5–8mg/kg PO once, up to 10mg/kg PO for 2
days (hookworms); 10 mg/kg q24h PO for 6–10 days
(microfilaricide); 0.5–2.0mg/kg 3 times/wk PO
(immunostimulant)

Cat: 4.4mg/kg PO once
Levetiracetem
500–4000 mg/d PO (divide bid or tid)
Levo-carnitine
Dog: 50mg/kg q8h PO
Cat: 250–500mg/cat qd PO
Levodopa (l-dopa)
Larodopa
Hepatic encephalopathy: 6.8 mg/kg initially, then 1.4mg/kg
q6h
Levothyroxine sodium
Soloxine
Thyro-Tabs
Synthroid
Dog: 0.01–0.02mg/kg q12h, PO
Cat: 0.01–0.02mg/kg q24h, PO
Lidocaine
Xylocaine
Antiarrhythmia in dog: 2–4mg/kg IV (maximum dose:
8mg/kg over 10 min); 25–75mg/kg/min IV infusion;
6mg/kg q1.5h IM
Cat: 0.25–0.75mg/kg IV, slowly
Lime sulfur (2–3% solution)
Topically once/wk for 4–6 weeks
Lincomycin
Lincocin
15–25mg/kg q12h IV, IM, PO
Liothyronine
Cytobin or Cytomel
4.4mg/kg q8h PO
Suppression testing: See Chapter 31 for protocol
Lisinopril
Prinivil
Dog: 0.25–0.5mg/kg q12–24h
Lithium carbonate
Lithotabs
Dog: 10mg/kg q12h PO
Cat: not recommended
1952 Appendix
Lomustine
60–90mg/m2 q21–28d PO
Loperamide
Imodium
Dog: 0.1–0.2mg/kg q8–12h PO
Cat: 0.1–0.3mg/kg q12–24h PO
Lufenuron
Program
Flea control
Dog: 10mg/kg q30d PO
Cat: 30mg/kg q30d PO
Coccidioidomycosis
5mg/kg PO q24h
Luteinizing hormone
See Gonadorelin
Magnesium citrate
Citroma, Citro-Nesia (U.S.)
Citro-Mag (Canada)
2–4ml/kg PO
Magnesium hydroxide
Milk of Magnesia
Antacid: 5–10 ml per dog or cat PO
Cathartic:

Dog: 15–50ml/dog PO
Cat: 2–6ml/cat q24h PO
Magnesium sulfate
Dog: 8–25 g/dog q24h PO
Cat: 2–5 g/cat q24h PO
Mannitol
Osmitrol
Diuretic: 1 g/kg of 5–25% solution IV
Glaucoma or CNS edema: 0.5–1.0